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Beneficial effects of L-carnitine in myoblastic C2C12 cells. View abstract. Biol.Trace Elem.Res 2012;150(1-3):42-48. 2003;79(2):292-300. View abstract. 1 First, take your CoQ10 with a meal. View abstract. J Am Med Assoc 1999;282:2305-12. View abstract. G.Ital.Cardiol. Hart AM, Wilson AD, Montovani C, et al. Merchant, R., Jain, A., Udani, A., Puri, V., and Kotian, M. L-carnitine in beta thalassemia. Shapira Y, Gutman A. View abstract. View abstract. View abstract. Muniyappa, R. Oral carnitine therapy and insulin resistance. View abstract. Ciacci C, Peluso G, Iannoni E, et al. Efficacy of L-propionylcarnitine treatment in patients with left ventricular dysfunction. 2-15-1981;96(3):263-270. Minerva Urol.Nefrol. Impact of L-carnitine on plasma lipoprotein(a) concentrations: A systematic review and meta-analysis of randomized controlled trials. Cheng, H. J. and Chen, T. [Clinical efficacy of combined L-carnitine and acetyl-L-carnitine on idiopathic asthenospermia]. 2005;28(2):141-152. View abstract. B., and Wang, Y. X. A randomized double blind versus placebo study. People with depression have low blood levels of a substance called acetyl-L-carnitine, according to a Stanford University School of Medicine scientist and her collaborators in a multicenter study. Hum.Reprod. Jpn J Clin Pharmacol Ther 1989;20(3):607-618. Clin Ter. Sigman, M., Glass, S., Campagnone, J., and Pryor, J. L. Carnitine for the treatment of idiopathic asthenospermia: a randomized, double-blind, placebo-controlled trial. Sotobatake I, Noda S, Hayashi H, and et al. Jing, L., Li, W. M., Zhou, L. J., and Song, J. El Sharkwy I, Sharaf El-Din M. l-Carnitine plus metformin in clomiphene-resistant obese PCOS women, reproductive and metabolic effects: a randomized clinical trial. Low Blood Pressure. 1996;24(4):251-255. View abstract. View abstract. We comply with the HONcode standard for trustworthy health information. LevOCARNitine (levOCARNitine)." 1. J Dermatol.Sci 2007;48(2):141-144. View abstract. View abstract. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. L-carnitine is technically FDA-approved for just one use: treating carnitine deficiency. A. Diagnosis, treatment and outcome of glutaric aciduria type I in Zhejiang Province, China. Passeri M, Cucinotta D, Bonati PA, et al. View abstract. 2012;7(11):1836-1842. Beneficial effects of L-carnitine in post dialysis syndrome. Rossignol, D. A. Chao, H. H., Chen, C. H., Liu, J. C., Lin, J. W., Wong, K. L., and Cheng, T. H. L-Carnitine attenuates angiotensin II-induced proliferation of cardiac fibroblasts: role of NADPH oxidase inhibition and decreased sphingosine-1-phosphate generation. View abstract. Reduction of serum carnitine concentrations during anticonvulsant therapy with phenobarbital, valproic acid, phenytoin, and carbamazepine in children. View abstract. Call your doctor at once if you have: a seizure (convulsions). View abstract. Nihon Rinsho 2007;65(6):1005-1010. Crentsil, V. Mechanistic contribution of carnitine deficiency to geriatric frailty. The effect of combined L-carnitine and erythropoietin administration on the anaemia and on the lipid profile of patients on hemodialysis [abstract]. Fertil.Steril. View abstract. In an eight-week study in 38 women who exercised four times per week, there was no difference in weight loss between those who took L-carnitine and those who didnt (24). An JH, Kim YJ, Kim KJ, et al. Zhao, J. L., Gao, D. Z., Liu, D., He, H. H., She, Q., and Yin, Y. H. Improvement of exercise tolerance by L-carnitine in patients with cardiac syndrome X. Chin.Hosp.Pharm.J. View abstract. Cui, G., Xu, W. H., and Wu.G.P. Int.J Cancer 9-15-2008;123(6):1227-1239. Clin Drug Investig. View abstract. The effect of preoperative L-carnitine supplementation on myocardial metabolism during aorto-coronary-bypass surgery. View abstract. A., Izquierdo, M. A., Jimeno, J., and Raymond, E. Reports of clinical benefit of plitidepsin (Aplidine), a new marine-derived anticancer agent, in patients with advanced medullary thyroid carcinoma. Lee, N. C., Tang, N. L., Chien, Y. H., Chen, C. A., Lin, S. J., Chiu, P. C., Huang, A. C., and Hwu, W. L. Diagnoses of newborns and mothers with carnitine uptake defects through newborn screening. Pittler, M. H. and Ernst, E. Complementary therapies for neuropathic and neuralgic pain: systematic review. Dragan, G. I., Vasiliu, A., Georgescu, E., and Dumas, I. Nagai, N., Kameda, N., Kobashi, R., Nishida, M., Horikawa, C., Egawa, K., Yoshimura, M., Kitagawa, Y., Abe, K., Kiso, Y., Sakane, N., Kotani, K., and Moritani, T. Effect of L-carnitine intake upon reduction of hunger feeling in young healthy females. 2010;14(4):498-504. Biogerontology. 2012;2:CD006659. 2010;55(6):384-389. Am J Cardiol 1997;79:777-80. L-acetylcarnitine in depressed elderly subjects. View abstract. Nutr J. View abstract. Wei G, Zhou Z, Cui Y, et al. However, you should always pick the form thats best for your personal needs and goals. Acenocoumarol is used to slow blood clotting. 2010;44(7-8):1287-1293. Natalie Rasgon. Nephrol Dial.Transplant. View abstract. Eur Heart J 1992;13:251-5. View abstract. View abstract. View abstract. View abstract. Dig.Dis Sci 2008;53(11):3018-3025. View abstract. Chen, J. C., Tsai, T. C., Liu, C. S., and Lu, C. T. Acute hearing loss in a patient with mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS). Deeks SG, Collier A, Lalezari J, et al. However, the human body is extremely complex, and the results of both human and animal studies are mixed (24, 25, 26, 27). View abstract. Turpeinen AK, Kuikka JT, Vanninen E, and et al. Shahidi M, Hashemi SR, Fattahi N, et al. Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Bartels GL, Remme WJ, Holwerda KJ, Kruijssen DA. de Lira-Garcia, C., Souto-Gallardo, M., Bacardi-Gascon, M., and Jimenez-Cruz, A. Z., and McIntyre, R. S. Acetyl-L-carnitine and alpha-lipoic acid: possible neurotherapeutic agents for mood disorders? L-carnitine decreases severity and type of fatigue induced by interferon-alpha in the treatment of patients with hepatitis C. Neuropsychobiology 2003;47:94-7. Dokmeci, D., Inan, M., Basaran, U. N., Yalcin, O., Aydogdu, N., Turan, F. N., and Uz, Y. H. Protective effect of L-carnitine on testicular ischaemia-reperfusion injury in rats. "L-carnitine and platelet aggregation in uremic patients subjected to hemodialysis." View abstract. Ann.Clin Psychiatry 2009;21(4):213-236. 4-5-2008;130(12):441-445. J.Altern.Complement Med. Nephron 1990;55(1):28-32. Nephrol.Dial.Transplant. Acta Anaesthesiol.Scand. Jeulin C, Lewin LM. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. [The anti-arrhythmic effect of L-carnitine in subjects with ischemic cardiopathy]. Efficacy of l-carnitine supplementation for management of blood lipids: A systematic review and dose-response meta-analysis of randomized controlled trials. Drug class: Nutraceutical products. Prolonged moderate-intensity exercise without and with L-carnitine supplementation in patients with MCAD deficiency. Capaldo B, Napoli R, Di Bonito P, et al. Rondanelli M, Opizzi A, Perna S, Faliva M, Solerte SB, Fioravanti M, Klersy C, Edda C, Maddalena P, Luciano S, Paola C, Emanuela C, Claudia S, Donini LM. Unexpected awakening from comatose thyroid storm after a single intravenous injection of L-carnitine. Am J Clin Nutr 1981;34(8):1496-1500. View abstract. Hum Reprod Update 1996;2:87-102. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Loffredo, L., Marcoccia, A., Pignatelli, P., Andreozzi, P., Borgia, M. C., Cangemi, R., Chiarotti, F., and Violi, F. Oxidative-stress-mediated arterial dysfunction in patients with peripheral arterial disease. In one study, 2 grams of L-carnitine reduced fatigue and increased muscle function in older adults. Am J Kidney Dis. Am.J Med.Genet.A 4-1-2008;146(7):803-812. L-Carnosine (-alanyl-L-histidine) is a dipeptide of the amino acids beta-alanine and histidine. Biagini, A., Opie, L., Rovai, D., Mazzei, M. G., Carpeggiani, C., and Maseri, A. Genazzani, A. D., Lanzoni, C., Ricchieri, F., Santagni, S., Rattighieri, E., Chierchia, E., Monteleone, P., and Jasonni, V. M. Acetyl-L-carnitine (ALC) administration positively affects reproductive axis in hypogonadotropic women with functional hypothalamic amenorrhea. 2008;(2):CD003917. Nutr Metab Cardiovasc Dis 2019;29(11):1151-67. doi: 10.1016/j.numecd.2019.07.012. View abstract. Cancer Chemother Pharmacol 1999;44:170-2. Wang DD, Wang TY, Yang Y, He SM, Wang YM. L-carnitine may help increase mitochondrial function, which plays a key role in disease and healthy aging (19, 20, 21). 2008;23(7):1602-1606. Written by Cerner Multum. View abstract. Loumbakis P, Anezinis P, Evangeliou A, and et al. View abstract. View abstract. l-Carnitine causes insomnia I've been taking l-Carnitine Fumarate in the evening and it's giving me serious insomnia. Arch Intern Med 1999;159:1143-4. Carnitine deficiency induced by pivampicillin and pivmecillinam therapy. Gentile V, Vicini P, Prigiotti G, et al. Acta Paediatr 1996;85:446-9. Megri K, Trombert JC Zannier A. Wang Y, Xu Y, Zou R, et al. Holme E, Greter J, Jacobson CE, et al. View abstract. View abstract. But doses of less than 3 grams a day seem safe for pretty much anyone. El Beshlawy, A., Abd, El Raouf, Mostafa, F., Talaat, M., Isma'eel, H., Aoun, E., Hoffbrand, A. V., and Taher, A. Diastolic dysfunction and pulmonary hypertension in sickle cell anemia: is there a role for L-carnitine treatment? Indian J Exp.Biol. Liu J, Head E, Kuratsune H, et al. Acta Neurol.Scand. Onofrj M, Fulgente T, Melchionda D, et al. Spiering, B. Trivelli G, Vitali P Girmenia S Castelli F. Trattamento della dislipidemia dell'emodializzato con L-carnitina. 2010;32(8):669-672. View abstract. The standard dose of L-carnitine is 5002,000 mg per day. Indian J Clin Biochem 1992;7:19-21. L-carnitine, ginseng, guarana, glucose, taurine, and more. J Pediatr 1986;109(6):984-988. View abstract. View abstract. Int J Clin Pharmacol Ther Toxicol 1988;26:217-20. A., and Morrow, G. R. Pharmacologic treatment of cancer-related fatigue. Famularo G, De Simone C, Cifone G. Carnitine stands on its own in HIV infection treatment. View abstract. Seattle, WA: University of Washington, Seattle;1993. Pons-Rejraji H, Brugnon F, Sion B, Maqdasy S, Gouby G, Pereira B, Marceau G, Gremeau AS, Drevet J, Grizard G, Janny L, Tauveron I.

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